How Free Radicals Works?

A simple example of free radicals which everyone has come across is when we cut an apple. Once an apple is cut, it can only last for a few minutes before the color change to brown. The once crispy, juicy beautiful apple flesh has turned into a wrinkly grey. This is how free radicals works!


Free radicals are capable to destroy enzymes, protein molecule and even a complete cell. Free radicals can multiply by process of a chain reaction. These reactive substances can harm cell structures so gravely, weaken the immunity system and altered DNA codes.

Recall on what happen to apple, the process is called oxidation. Likewise, if our cells are left unprotected, a similar process might take place inside the body, causes our cells and tissues unable to function properly, eventually causing unpredictable damages. In another word, free radicals may have serious out-turn to our health.

“Free radicals are produced in cells by cellular metabolism and by exogenous agents. These species react with biomolecules in cells, including DNA. The resulting damage to DNA, which is also called oxidative damage to DNA, is implicated in mutagenesis, carcinogenesis, and aging” – article: https://www.ncbi.nlm.nih.gov/pubmed/12031895



We Can’t Avoid Free Radicals!

Truth to be told, we can’t avoid free radicals because free radicals are produced within the body as natural by-products of ongoing biochemical reaction during metabolism activities, detoxification processes and when the body are fighting against infections or viruses. When these by-products (or also known as waste products) built up, it may cause harm to the body.



Worsen With Free Radicals Generating Substances

It worsens with the existence of free radicals generating substances which can be found in what we eat, drink, environment that we breath in, touch and unhealthy lifestyle. For instance, we knew chicken and other poultry are injected with antibiotic and hormone contributing to more free radicals. Same goes to pesticides in fruits and vegetables. 

 


Free Radicals Are Undeniably Dangerous 

Free radicals are undeniably dangerous. A serious example is, aging before your age. Have you ever come across someone who is in his 20s but look like 40 years old? Free radicals are the culprit, causing the body new cells to grow incorrectly, thus leading to aging.  



Lower Antioxidant Level produced as we aged

We can’t avoid free radicals, however we can prevent and minimize the damages caused by free radicals. Antioxidants keep free radicals under control. Antioxidants are molecules in our cells that prevent free radicals from stealing electrons and making damage. Our body did produce antioxidant enzymes on its own. However as we ages, antioxidants level produces in the body are decreasing and it is insufficient to fight against free radicals.




We need Comprehensive Solutions to Fight Free Radicals

SOD, CAT and GPx are the antioxidant enzymes produce by our body. These are the Master of Antioxidative Enzymes (MAE) that fight against free radicals in a unique way where it will renew after fight against one radical to fight more coming free radicals. 

After years of research, scientists from Spain succeeded in finding solution to our body defense system from free radicals. From the ocean, this new breakthrough allowed the discovery of strong cellular defence and self-repairing capability. Thus, it was also linked to discovery of how our body fight free radicals from these processes. 

The product from the ocean is a microalgae, formulated as TetraSOD with three complete antioxidative enzymes (SOD, CAT and GPx) in natural form to fight free radicals. Therefore, successful defense on free radicals and prevent altering of DNA.



References

Chatgilialoglu, C., & O'Neill, P. (2001). Free radicals associated with DNA damage. Experimental gerontology, 36(9), 1459-1471.

Dizdaroglu, M., Jaruga, P., Birincioglu, M., & Rodriguez, H. (2002). Free radical-induced damage to DNA: mechanisms and measurement. Free Radical Biology and Medicine, 32(11), 1102-1115.

Floyd, R. A., & Carney, J. M. (1992). Free radical damage to protein and DNA: mechanisms involved and relevant observations on brain undergoing oxidative stress. Annals of Neurology: Official Journal of the American Neurological Association and the Child Neurology Society, 32(S1), S22-S27.

Valko, M., Izakovic, M., Mazur, M., Rhodes, C. J., & Telser, J. (2004). Role of oxygen radicals in DNA damage and cancer incidence. Molecular and cellular biochemistry, 266(1-2), 37-56.

Pacifici, R. E., & Davies, K. J. (1991). Protein, lipid and DNA repair systems in oxidative stress: the free-radical theory of aging revisited. Gerontology, 37(1-3), 166-180.

Willson, R. L. (1970). The reaction of oxygen with radiation-induced free radicals in DNA and related compounds. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, 17(4), 349-358.

Barja, G. (2004). Free radicals and aging. Trends in neurosciences, 27(10), 595-600.

Moskovitz, J., Yim, M. B., & Chock, P. B. (2002). Free radicals and disease. Archives of Biochemistry and Biophysics, 397(2), 354-359.

Proctor, P. H., & Reynolds, E. S. (1984). Free radicals and disease in man. Physiol Chem Phys Med NMR, 16(3), 175-195.

Krajcovicova-Kudlackova, M., Ursinyova, M., Blazicek, P., Spustova, V., Ginter, E., Hladikova, V., & Klvanova, J. (2003). Free radical disease prevention and nutrition. Bratislavske lekarske listy, 104(2), 64-68.

Hu, H. L., Forsey, R. J., Blades, T. J., Barratt, M. E., Parmar, P., & Powell, J. R. (2001). Antioxidants may contribute in the fight against ageing: an in vitro model. Mechanisms of ageing and development, 121(1-3), 217-230.

Shinde, A., Ganu, J., & Naik, P. (2012). Effect of free radicals & antioxidants on oxidative stress: a review. Journal of Dental and Allied Sciences, 1(2), 63.